2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine

Base Information

Chemical Name:2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine
CAS No.:1296201-72-3
Molecular Formula:C₁₀H₁₃ClN₂Si
Molecular Weight:224.765
Hs Code.:2933399990
Mol file:1296201-72-3.mol

Synonyms:2-chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine

Suppliers and Price of 2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine >95%
500mg
$ 325.00

Matrix Scientific
2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine >95%
1g
$ 435.00

Crysdot
2-Chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine 97%
1g
$ 401.00

Chemenu
2-Chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine 97%
1g
$ 379.00

Total 2 raw suppliers

Chemical Property of 2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine

There total 2 articles about 2-Chloro-5-[2-(trimethylsilyl)ethynyl]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 800402-12-4
2-chloro-4-amino-5-iodopyridine

: 1066-54-2
trimethylsilylacetylene

: 1296201-72-3
2-chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 150 ℃; for 1h;

Reference yield:

: 14432-12-3
4-Amino-2-chloropyridine

: 1296201-72-3
2-chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium acetate; Iodine monochloride / acetic acid / 4 h / Reflux

2.1: triethylamine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / 0.17 h / Inert atmosphere

2.2: 16 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium acetate; Iodine monochloride; triethylamine; In acetic acid;

Reference yield: 85.0%

: 1296201-72-3
2-chloro-5-((trimethylsilyl)ethynyl)pyridin-4-amine

: 74976-31-1
6-chloro-1H-pyrrolo[3,2-c]pyridine

Guidance literature:: With potassium tert-butylate; In N,N-dimethyl-formamide; at 160 ℃; for 0.833333h; Inert atmosphere; Microwave irradiation;