1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI)

Base Information

• Chemical Name: 1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI)
• CAS No.: 294659-27-1
• Molecular Formula: C₆H₈O₅
• Molecular Weight: 160.127
• Mol file: 294659-27-1.mol

Synonyms:1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI)

Chemical Property of 1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI)

There total 4 articles about 1,3-Dioxolane-4-carboxylicacid,2,2-dimethyl-5-oxo-,(4S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dion (7270-63-5) → 2,2-dimethyl-5-oxo-1,3-dioxolane-4-carboxylic acid (62609-78-3,294659-27-1)

Guidance literature:

With water; In tetrahydrofuran; at 20 ℃; for 0.666667h; UV-irradiation;

DOI:10.1021/ja037637d

Reference yield: 56.0%

5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dion (7270-63-5) → 6,6-dimethyl-4,8-dioxo-5,7-dioxa-1,2-diazaspiro<2.5>oct-1-ene (68695-08-9) + cycl-isopropylidene malonate (2033-24-1) + tartronic acid (80-69-3) + malonic acid (141-82-2) + 2,2-dimethyl-5-oxo-1,3-dioxolane-4-carboxylic acid (62609-78-3,294659-27-1)

Guidance literature:

In tetrahydrofuran; water; for 3.5h; Product distribution; Irradiation;

DOI:10.1007/BF00506661

Reference yield: 31.0%

5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dion (7270-63-5) → 6,6-dimethyl-4,8-dioxo-5,7-dioxa-1,2-diazaspiro<2.5>oct-1-ene (68695-08-9) + cycl-isopropylidene malonate (2033-24-1) + 2,2-dimethyl-5-oxo-1,3-dioxolane-4-carboxylic acid (62609-78-3,294659-27-1)

Guidance literature:

In tetrahydrofuran; water; at 18 - 20 ℃; Further Variations:; Solvents; UV wavelength; Product distribution; UV-irradiation;

DOI:10.1134/S1070428006060029

upstream raw materials:

5-diazo-2,2-dimethyl-1,3-dioxane-4,6-dion

2,2-dimethyl-5-oxomethylidene-1,3-dioxolan-4-one

Downstream raw materials:

4-oxo-2,2-dimethyl-1,3-dioxolane