1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine

Base Information

Chemical Name:1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine
CAS No.:199938-29-9
Molecular Formula:C₃₁H₄₈N₂O₄Si
Molecular Weight:540.819
Hs Code.:

Synonyms:1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine

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Technology Process of 1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine

There total 2 articles about 1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 199938-28-8
1-(tert-butyloxycarbonyl)-4-(3-phenyl-3-oxopropyl)homopiperazine

: 117973-14-5
3-(tert-butyldimethylsilyloxy)phenylmagnesium bromide

: 199938-29-9
1-(tert-butyloxycarbonyl)-4-[3-{3-(tert-butyldimethylsilyloxy)phenyl}-3-hydroxy-3-phenylpropyl]homopiperazine

Guidance literature:: 1-(tert-butyloxycarbonyl)-4-(3-phenyl-3-oxopropyl)homopiperazine; 3-(tert-butyldimethylsilyloxy)phenylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

With water; ammonium chloride; In tetrahydrofuran; at 20 ℃; for 0.25h;