2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

Base Information

• Chemical Name: 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine
• CAS No.: 245074-30-0
• Molecular Formula: C₂₄H₂₇N₅O₇
• Molecular Weight: 497.508

Synonyms:2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

Chemical Property of 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

There total 1 articles about 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

Benzoic acid (3aR,6R,7R,7aR)-6-(6-allyloxy-2-isobutyrylamino-purin-9-yl)-2-(4-methoxy-phenyl)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-yl ester → 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N2-isobutyryl-6-[(prop-2-enyl)oxy]purine (245074-30-0)

Guidance literature:

With trifluoroacetic acid; In methanol; at 20 ℃; for 1.5h;

DOI:10.1002/hlca.200390349

Reference yield: 85.0%

4,4'-dimethoxytrityl chloride (40615-36-9) + 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N2-isobutyryl-6-[(prop-2-enyl)oxy]purine (245074-30-0) → 2-amino-9-{2'-O-benzoyl-4'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-β-D-ribopyranosyl}-N2-isobutyryl-6-[(prop-2-enyl)oxy]purine (245074-35-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/hlca.200390349

Reference yield:

2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N2-isobutyryl-6-[(prop-2-enyl)oxy]purine (245074-30-0) → 2-amino-9-{3'-O-benzoyl-4'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-β-D-ribopyranosyl}-N2-isobutyryl-6-[(prop-2-enyl)oxy]purine (221170-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / 4A MS; EtN(i-Pr)2 / CH₂Cl₂ / 1 h / 20 °C

2: 80 percent / 4-nitrophenol; DMAP; Et₃N / pyridine; propan-1-ol / 60 h / 60 °C

With dmap; 4-nitro-phenol; triethylamine; N-ethyl-N,N-diisopropylamine; In pyridine; propan-1-ol; dichloromethane;

DOI:10.1002/hlca.200390349

Downstream raw materials:

2-amino-9-{2'-O-benzoyl-4'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-β-D-ribopyranosyl}-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

2-amino-9-{3'-O-benzoyl-4'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-β-D-ribopyranosyl}-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 245074-30-0 2-amino-9-(2'-O-benzoyl-β-D-ribopyranosyl)-N²-isobutyryl-6-[(prop-2-enyl)oxy]purine

Send

Send

Metric Ton KG G Pound L ML

Send

Send