N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Base Information

Chemical Name:N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester
CAS No.:170124-03-5
Molecular Formula:C₂₆H₄₁NO₆SSi
Molecular Weight:523.766
Hs Code.:

Synonyms:N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Suppliers and Price of N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

There total 4 articles about N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 88188-06-1
trimethyl((trifluoromethyl)sulfonyl)silane

: 869884-89-9
N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-oxo-1-buten-2-yl>-L-tyrosine methyl ester

: 170124-03-5
N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Guidance literature:: With triethylamine; In diethyl ether; 1.) 0 deg C, 40 min, 2.) 0 deg C, 4 h;
DOI:10.1021/jo00124a010

Reference yield:

: 4326-36-7
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

: 170124-03-5
N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / K₂CO₃ / acetone / Heating

2: 53 percent / Heating

3: 69 percent / p-TsOH*H₂O / benzene / 24 h / Heating

4: 98 percent / Et₃N / diethyl ether / 1.) 0 deg C, 40 min, 2.) 0 deg C, 4 h

With potassium carbonate; toluene-4-sulfonic acid; triethylamine; In diethyl ether; acetone; benzene;
DOI:10.1021/jo00124a010

Reference yield:

: 170124-00-2
N-(tert-Butyloxycarbonyl)-O-(2-oxopropyl)-L-tyrosine methyl ester

: 170124-03-5
N-(tert-Butyloxycarbonyl)-O-<1-(butylthio)-3-<(trimethylsilyl)oxy>-1,3-butadien-2-yl>-L-tyrosine methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 53 percent / Heating

2: 69 percent / p-TsOH*H₂O / benzene / 24 h / Heating

3: 98 percent / Et₃N / diethyl ether / 1.) 0 deg C, 40 min, 2.) 0 deg C, 4 h

With toluene-4-sulfonic acid; triethylamine; In diethyl ether; benzene;
DOI:10.1021/jo00124a010