4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

Base Information

• Chemical Name: 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester
• CAS No.: 190786-08-4
• Molecular Formula: C₂₁H₂₃NO₅
• Molecular Weight: 369.417

Synonyms:4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

Chemical Property of 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

There total 4 articles about 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4-fluorobenzaldehyde (459-57-4) + 4-(2-{1-[(E)-Hydroxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester (190786-06-2) → 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester (190786-08-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran; dimethyl sulfoxide; Ambient temperature;

DOI:10.1016/S0960-894X(98)00001-8

Reference yield:

Ethyl 4-bromobutyrate (2969-81-5) → 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester (190786-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / NaH / dimethylformamide / 50 °C

2: 92 percent / NH₂OH*HCl, NaOAc / ethanol; H₂O / Heating

With hydroxylamine hydrochloride; sodium acetate; sodium hydride; In ethanol; water; N,N-dimethyl-formamide;

DOI:10.1016/S0960-894X(98)00001-8

Reference yield:

o-hydroxyacetophenone (118-93-4,104809-67-8) → 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester (190786-08-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / NaH / dimethylformamide / 50 °C

2: 92 percent / NH₂OH*HCl, NaOAc / ethanol; H₂O / Heating

3: 50 percent / NaH / tetrahydrofuran; dimethylsulfoxide / Ambient temperature

With hydroxylamine hydrochloride; sodium acetate; sodium hydride; In tetrahydrofuran; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide;

DOI:10.1016/S0960-894X(98)00001-8

upstream raw materials:

4-fluorobenzaldehyde

4-(2-{1-[(E)-Hydroxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

Ethyl 4-bromobutyrate

o-hydroxyacetophenone

Downstream raw materials:

2-<2-(3-ethoxycarbonyl-1-propyloxy)phenyl>-5-formylbenzofuran

2-<2-(3-ethoxycarbonyl-1-propyloxy)phenyl>benzofuran-5-carboxylic acid

N-diphenylmethyl-2-<2-(3-ethoxycarbonyl-1-propyloxy)phenyl>benzofuran-5-carboxamide

4-[2-(5-{[bis-(4-methoxy-phenyl)-methyl]-carbamoyl}-benzofuran-2-yl)-phenoxy]-butyric acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 190786-08-4 4-(2-{1-[(E)-4-Formyl-phenoxyimino]-ethyl}-phenoxy)-butyric acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send