(R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate

Base Information

• Chemical Name: (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate
• CAS No.: 1264240-09-6
• Molecular Formula: C₂₃H₂₄FNO₆
• Molecular Weight: 429.445

Synonyms:(R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate

Chemical Property of (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate

Chemical Property:

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Technology Process of (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate

There total 1 articles about (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

→ (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate (1264240-09-6)

Guidance literature:

Reference yield: 67.0%

allyl N-2-[(2S,4R)-4-[(tert-butoxycarbonyl)-amino]-2-(hydroxymethyl)tetrahydro-1H-pyrrol-1-yl]-2-oxoethyl-N-methylcarbamate (1264241-01-1) + (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate (1264240-09-6) → C40H51FN4O11 (1264241-60-2)

Guidance literature:

With cyanomethylenetributyl-phosphorane; In toluene;

Reference yield: 56.0%

tert-butyl (3R)-4-{2-[[(allyloxy)carbonyl]-(methyl)amino]acetyl}-3-(hydroxymethyl)tetrahydro-1(2H)-pyrazinecarboxylate (1264241-05-5) + (R)-5-allyl 1-benzyl 2-(5-fluoro-2-hydroxy-N-methylbenzamido)pentanedioate (1264240-09-6) → C40H51FN4O11 (1264241-90-8)

Guidance literature:

With cyanomethylenetributyl-phosphorane; In toluene; Reflux;

Downstream raw materials:

C₄₀H₅₁FN₄O₁₁

C₄₀H₅₁FN₄O₁₁

C₃₃H₄₃FN₄O₉

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