tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate

Base Information

Chemical Name:tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate
CAS No.:291533-28-3
Molecular Formula:C11H21 N O3
Molecular Weight:215.28934
Hs Code.:
European Community (EC) Number:803-672-0
Nikkaji Number:J982.185F
Mol file:291533-28-3.mol

Synonyms:291533-28-3;tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate;TERT-BUTYL N-[(1R,2S)-2-HYDROXYCYCLOHEXYL]CARBAMATE;296778-53-5;tert-butyl (1R,2S)-2-hydroxycyclohexylcarbamate;Rel-tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbamate;Carbamic acid, N-[(1R,2S)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester;MFCD11975366;Carbamic acid, [(1R,2S)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester;SCHEMBL25981800;AMY37619;AKOS027323888;(1R,2S)-2-(Boc-amino)-cyclohexanol;AT34240;Carbamic acid, [(1R,2S)-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester (9CI);BS-42769;CS-0183498;(1R,2S)-1-(Boc-amino)-2-hydroxycyclohexane;V10052;EN300-7171235;EN300-7548435;J-524337;TERT-BUTYL (CIS-2-HYDROXYCYCLOHEXYL)CARBAMATE;(1S,2R)-cis-N-Boc-2-aminocyclohexanol, >=97% (GC);tert-butyl N-[(1R, 2S)-2-hydroxycyclohexyl]carbamate;rac-tert-butyl N-[(1R,2S)-2-hydroxycyclohexyl]carbamate

Suppliers and Price of tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(1S,2R)-cis-N-Boc-2-aminocyclohexanol ≥97% (GC)
250mg
$ 129.00

Sigma-Aldrich
(1S,2R)-cis-N-Boc-2-aminocyclohexanol ≥97% (GC)
1g
$ 399.00

Crysdot
tert-Butyl((1R,2S)-2-hydroxycyclohexyl)carbamate 95+%
1g
$ 352.00

Total 9 raw suppliers

Chemical Property of tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate

Chemical Property:

PSA：58.56000
LogP:2.20550
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:215.15214353
Heavy Atom Count:15
Complexity:222

Purity/Quality:

97% ^*data from raw suppliers

(1S,2R)-cis-N-Boc-2-aminocyclohexanol ≥97% (GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CCCCC1O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H]1CCCC[C@@H]1O

Technology Process of tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate

There total 9 articles about tert-butyl ((1R,2S)-2-hydroxycyclohexyl)carbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: cis-2-amino-cyclohexanol hydrochloride

: 291533-28-3,477584-30-8
(1S,2R)-2-(tert-butoxycarbonylamino)cyclohexan-1-ol

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;
DOI:10.1002/ardp.202100362

Reference yield:

: 291533-10-3
2-(tert-butoxycarbonylamino)cyclohexanone

: 214679-17-1,477584-30-8
(1S,2R)-(-)-1-tert-butoxycarbonylaminocyclohexan-2-ol

: 291533-28-3,477584-30-8
(1S,2R)-2-(tert-butoxycarbonylamino)cyclohexan-1-ol

Guidance literature:: With potassium hydroxide; trans-RuCl₂[(R)-xylbinap][(S)-daipen]; hydrogen; In isopropyl alcohol; at 25 ℃; for 5h; under 6080.41 Torr; Title compound not separated from byproducts.;
DOI:10.1021/ja001098k