(S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester

Base Information

• Chemical Name: (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester
• CAS No.: 112700-19-3
• Molecular Formula: C₃₀H₅₁NO₄
• Molecular Weight: 489.739
• Mol file: 112700-19-3.mol

Synonyms:(S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester

Chemical Property of (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester

Chemical Property:

Purity/Quality:

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Technology Process of (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester

There total 1 articles about (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-Hexadecanol (36653-82-4,124-29-8) + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → (S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester (112700-19-3)

Guidance literature:

With Isopropenyl chloroformate; triethylamine; dmap; In dichloromethane; at 0 ℃;

DOI:10.1016/S0040-4039(00)95387-5

Reference yield:

(S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester (112700-19-3) → hexadecyl L-phenylalaninate (692731-62-7)

Guidance literature:

(S)-2-tert-Butoxycarbonylamino-3-phenyl-propionic acid hexadecyl ester; With trifluoroacetic acid; In dichloromethane; for 2h;

With sodium carbonate; In water; ethyl acetate;

DOI:10.1039/c0cc02464c

upstream raw materials:

1-Hexadecanol

N-tert-butoxycarbonyl-L-phenylalanine

Downstream raw materials:

hexadecyl L-phenylalaninate