Technology Process of cis-PdMePh(PEt2Ph)2
There total 3 articles about cis-PdMePh(PEt2Ph)2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
methanol; methyllithium;
In
diethyl ether;
byproducts: MeOLi, methane, PEt2Ph; under N2, Ar or vac.; addn. of excess MeLi (5 times) to mixt. of trans-PdPh(Br)(PEt2Ph)2 and Et2O, contg. styrene, at -40°C; stirred 1h at 20°C; cooled to -70°C; addn. of Et2O soln of MeOH (LiOMe); filtered at -30°C; concd. to dryness; dissolved in Et2O/pentane (1:4, -20°C);stirred at -40°C; pptn.; recrystn. from cold Et2O/pentane (4:1, small amt. of styrene); pptn.; elem. anal.;
DOI:10.1021/om00103a023
- Guidance literature:
-
With
methyllithium;
In
diethyl ether;
byproducts: LiBr; under Ar, N2 or vac.; addn. of Et2O soln. of MeLi to heterogeneous mixt. of trans-PdPh(Br)(PEt2Ph)2 and Et2O contg. styrene at -70°C; stirred at -10 to 0°C, 2h; addn. of dioxane at -30°C (pptn. of LiBr); filtered at -40°C; concn.; addn. of hexane at -70°C; pptn.; recrystn. (Et2O; some styrene; <-10°C to remove cis-PdMePh(PEt2Ph)2); pptn.; elem. anal.;
DOI:10.1021/om00103a023
- Guidance literature:
-
In
diethyl ether;
