3-acetyl-isoaltholactone

Base Information

Chemical Name:3-acetyl-isoaltholactone
CAS No.:474126-25-5
Molecular Formula:C₁₅H₁₄O₅
Molecular Weight:274.273
Hs Code.:

Synonyms:3-acetyl-isoaltholactone

Suppliers and Price of 3-acetyl-isoaltholactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 3-acetyl-isoaltholactone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 3-acetyl-isoaltholactone

There total 10 articles about 3-acetyl-isoaltholactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 474126-24-4
(3S,6S)-3-acetyl-6-(1-ethoxyethoxy)-isoaltholactone

: 474126-25-5
3-acetyl-isoaltholactone

Guidance literature:: With chromium(VI) oxide; acetic acid; at 25 ℃; for 5h;
DOI:10.1016/S0040-4020(02)00791-3

Reference yield:

: 129694-45-7
(2S)-6-Hydroxy-2-<(E)-styryl>-6H-pyran-3(2H)-one

: 474126-25-5
3-acetyl-isoaltholactone

Guidance literature:: Multi-step reaction with 10 steps

1: 74 percent / pyridinium toluene-p-sulphonate / CH₂Cl₂ / 3 h / 25 °C

2: 78 percent / NaBH₄; CeCl₃*7H₂O / methanol / -40 - 20 °C

3: 2.8 g / Ph₃P; DEAD / tetrahydrofuran / 0 - 20 °C

4: 82 percent / K₂CO₃ / methanol / 10 h / 20 °C

5: 95 percent / Et₃N; DMAP / CH₂Cl₂ / 8 h / 0 °C

6: 82 percent / NaHCO₃; p-CPBA / CH₂Cl₂ / 10 h / 25 °C

7: 80 percent / TBAF / tetrahydrofuran / 2 h / 25 °C

8: 90 percent / PPTS / CH₂Cl₂ / 4 h / 25 °C

9: 92 percent / 4-dimethylaminopyridine; pyridine / CH₂Cl₂ / 5 h / 25 °C

10: 83 percent / CrO₃; HOAc / 5 h / 25 °C

With pyridine; chromium(VI) oxide; dmap; sodium tetrahydroborate; cerium(III) chloride; p-chloroperbenzoic acid; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; sodium hydrogencarbonate; potassium carbonate; acetic acid; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; 3: Mitsunobu reaction;
DOI:10.1016/S0040-4020(02)00791-3

Reference yield:

: 129694-46-8
(2S,6S)-6-(1-Ethoxyethoxy)-2-<(E)-styryl>-6H-pyran-3(2H)-one

: 474126-25-5
3-acetyl-isoaltholactone

Guidance literature:: Multi-step reaction with 9 steps

1: 78 percent / NaBH₄; CeCl₃*7H₂O / methanol / -40 - 20 °C

2: 2.8 g / Ph₃P; DEAD / tetrahydrofuran / 0 - 20 °C

3: 82 percent / K₂CO₃ / methanol / 10 h / 20 °C

4: 95 percent / Et₃N; DMAP / CH₂Cl₂ / 8 h / 0 °C

5: 82 percent / NaHCO₃; p-CPBA / CH₂Cl₂ / 10 h / 25 °C

6: 80 percent / TBAF / tetrahydrofuran / 2 h / 25 °C

7: 90 percent / PPTS / CH₂Cl₂ / 4 h / 25 °C

8: 92 percent / 4-dimethylaminopyridine; pyridine / CH₂Cl₂ / 5 h / 25 °C

9: 83 percent / CrO₃; HOAc / 5 h / 25 °C

With pyridine; chromium(VI) oxide; dmap; sodium tetrahydroborate; cerium(III) chloride; p-chloroperbenzoic acid; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; sodium hydrogencarbonate; potassium carbonate; acetic acid; triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; 2: Mitsunobu reaction;
DOI:10.1016/S0040-4020(02)00791-3