Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)

Base Information

Chemical Name:Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)
CAS No.:288314-21-6
Molecular Formula:C11H18 F N O2
Molecular Weight:215.2645232
Hs Code.:
Mol file:288314-21-6.mol

Synonyms:Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)

Suppliers and Price of Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)

Chemical Property:

PSA：49.66000
LogP:2.65540

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI)

There total 2 articles about Cyclohexanecarbonyl fluoride, 2-[(propylamino)carbonyl]-, (1R,2R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 288314-19-2
(1R,2R)-cyclohexane-1,2-dicarboxylic acid mono-n-propylamide

: 288314-21-6
(1R,2R)-2-Propylcarbamoyl-cyclohexanecarbonyl fluoride

Guidance literature:: With pyridine; trifluoro-[1,3,5]triazine; In dichloromethane; for 1.5h;
DOI:10.1016/S0040-4020(00)00252-0

Reference yield:

: 85-42-7,13149-00-3,14166-21-3,31982-85-1,71749-03-6,97233-90-4
trans-1,2-cyclohexanedicarboxylic anhydride

: 288314-21-6
(1R,2R)-2-Propylcarbamoyl-cyclohexanecarbonyl fluoride

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / CH₂Cl₂ / 2 h

2: 97 percent / pyridine; cyanuric fluoride / CH₂Cl₂ / 1.5 h

With pyridine; trifluoro-[1,3,5]triazine; In dichloromethane; 1: Ring cleavage / 2: Fluorination;
DOI:10.1016/S0040-4020(00)00252-0