dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate

Base Information

• Chemical Name: dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate
• CAS No.: 222417-79-0
• Molecular Formula: C₃₇H₄₁O₉P
• Molecular Weight: 660.701

Synonyms:dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate

Chemical Property of dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate

There total 4 articles about dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

(2S,3S,4S,5S,6S)-3,4,5,6-Tetrakis-benzyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester (253596-63-3) + dimethyl methane phosphonate (756-79-6) → dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate (222417-79-0)

Guidance literature:

dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

(2S,3S,4S,5S,6S)-3,4,5,6-Tetrakis-benzyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1080/07328309908544046

Reference yield:

benzyl 2,3,4-tri-O-benzyl-α-D-mannopyranoside (57783-76-3) → dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate (222417-79-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: CrO₃; H₂SO₄

3.1: butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C

3.2: 75 percent / tetrahydrofuran; hexane / -78 - 20 °C

With chromium(VI) oxide; n-butyllithium; sulfuric acid; In tetrahydrofuran; hexane; 1.1: Oxidation / 2.1: Methylation / 3.1: Metallation / 3.2: Substitution;

DOI:10.1080/07328309908544046

Reference yield:

benzyl 2,3,4-tri-O-benzyl-α-D-mannopyranuronic acid (858352-14-4) → dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate (222417-79-0)

Guidance literature:

Multi-step reaction with 2 steps

2.1: butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C

2.2: 75 percent / tetrahydrofuran; hexane / -78 - 20 °C

With n-butyllithium; In tetrahydrofuran; hexane; 1.1: Methylation / 2.1: Metallation / 2.2: Substitution;

DOI:10.1080/07328309908544046

upstream raw materials:

(2S,3S,4S,5S,6S)-3,4,5,6-Tetrakis-benzyloxy-tetrahydro-pyran-2-carboxylic acid methyl ester

dimethyl methane phosphonate

methylphosphonic acid dimethyl ester; deprotonated form

benzyl 2,3,4-tri-O-benzyl-α-D-mannopyranoside

Downstream raw materials:

3-O-benzyl-5-deoxy-5-C-[benzyl 2,3,4-tri-O-benzyl-7-deoxy-α-D-manno-heptopyranosid-6-ulose-7(E)-ylidene]-1,2-O-isopropylidene-α-D-xylofuranose

3-O-benzyl-5-deoxy-5-C-[benzyl 2,3,4-tri-O-benzyl-7-deoxy-D-glycero-α-D-manno-heptopyranosid-7(E)-ylidene]-1,2-O-isopropylidene-α-D-xylofuranose

benzyl 2,3,4,6-tetra-O-benzyl-7,8-dideoxy-7(E)-eno-9,10:11,12-di-O-isopropylidene-D-gluco-α-D-manno-dodeca-1,5-pyranoside

benzyl 2,3,4-tri-O-benzyl-7,8-dideoxy-7(E)-eno-9,10:11,12-di-O-isopropylidene-D-gluco-α-D-manno-dodeca-1,5-pyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 222417-79-0 dimethyl (benzyl 2,3,4-tri-O-benzyl-α-D-manno-heptopyranos-6-ulos-7-yl)phosphonate

Send

Send

Metric Ton KG G Pound L ML

Send

Send