ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Base Information

Chemical Name:ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate
CAS No.:1421015-79-3
Molecular Formula:C₃₀H₃₂ClNO₅
Molecular Weight:522.041
Hs Code.:

Synonyms:ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Suppliers and Price of ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

There total 4 articles about ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₀H₃₀ClNO₆

: 1421015-79-3
ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmc.2012.12.002

Reference yield:

: 575504-26-6
5-methyl-7-nitroindan-4-ol

: 1421015-79-3
ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Guidance literature:: Multi-step reaction with 5 steps

1: copper; triethylamine / dichloromethane / 120 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C

3: pyridine / dichloromethane / 3 h / 20 °C

4: trifluoromethylsulfonic anhydride / dichloromethane / 15 h / 20 °C

5: triethylsilane; trifluoroacetic acid / dichloromethane / 20 °C

With pyridine; triethylsilane; trifluoromethylsulfonic anhydride; palladium 10% on activated carbon; hydrogen; copper; triethylamine; trifluoroacetic acid; In dichloromethane; ethyl acetate; 4: |Friedel-Crafts Acylation;
DOI:10.1016/j.bmc.2012.12.002

Reference yield:

: bis(4-methoxyphenyl)iodonium tetrafluoroborate

: 1421015-79-3
ethyl N-(7-{3-[2-(4-chlorophenyl)ethyl]-4-methoxyphenoxy}-6-methylindan-4-yl)malonamate

Guidance literature:: Multi-step reaction with 5 steps

1: copper; triethylamine / dichloromethane / 120 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C

3: pyridine / dichloromethane / 3 h / 20 °C

4: trifluoromethylsulfonic anhydride / dichloromethane / 15 h / 20 °C

5: triethylsilane; trifluoroacetic acid / dichloromethane / 20 °C

With pyridine; triethylsilane; trifluoromethylsulfonic anhydride; palladium 10% on activated carbon; hydrogen; copper; triethylamine; trifluoroacetic acid; In dichloromethane; ethyl acetate; 4: |Friedel-Crafts Acylation;
DOI:10.1016/j.bmc.2012.12.002