(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Base Information

Chemical Name:(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester
CAS No.:522617-85-2
Molecular Formula:C₂₇H₃₀O₄
Molecular Weight:418.533
Hs Code.:

Synonyms:(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Suppliers and Price of (E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

There total 3 articles about (E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 10283-91-7
cis-cyclopentane-1,3-dicarboxaldehyde

: 208182-09-6
phenethyl diisopropyl phosphonate

: 522617-85-2
(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Guidance literature:: phenethyl diisopropyl phosphonate; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 2h;

cis-cyclopentane-1,3-dicarboxaldehyde; In tetrahydrofuran; at -78 - 4 ℃; Further stages.;
DOI:10.1021/ja003712y

Reference yield:

: 498-66-8
norborn-2-ene

: 522617-85-2
(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. K₃Fe(CN)6; K₂OsO₄; quinuclidine / K₂CO₃ / 2-methyl-propan-2-ol

2.1: aq. NaIO₄ / tetrahydrofuran / 0 - 20 °C

3.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

3.2: 90 percent / tetrahydrofuran / -78 - 4 °C

With Quinuclidine; potassium osmate(VI); sodium periodate; potassium tert-butylate; potassium hexacyanoferrate(III); potassium carbonate; In tetrahydrofuran; tert-butyl alcohol; 1.1: Sharpless dihydroxylation / 3.2: Horner-Wadsworth-Emmons reaction;
DOI:10.1021/ja003712y

Reference yield:

: 14440-78-9
2,3-dihydroxybicyclo[2.2.1]hept-5-an

: 522617-85-2
(E)-3-[(1R,3S)-3-((E)-2-Phenethyloxycarbonyl-vinyl)-cyclopentyl]-acrylic acid phenethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. NaIO₄ / tetrahydrofuran / 0 - 20 °C

2.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

2.2: 90 percent / tetrahydrofuran / -78 - 4 °C

With sodium periodate; potassium tert-butylate; In tetrahydrofuran; 2.2: Horner-Wadsworth-Emmons reaction;
DOI:10.1021/ja003712y