Technology Process of methyl-(1-phenylsulfonylindolizin-2-yl)amine
There total 7 articles about methyl-(1-phenylsulfonylindolizin-2-yl)amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
Cooling;
Reflux;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: caesium carbonate; cesium fluoride / N,N-dimethyl-formamide / 20 - 60 °C / Inert atmosphere
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / -5 - 0 °C
3.1: tetrahydrofuran / 18 h / Reflux
3.2: 24 h / Reflux
4.1: potassium hydroxide; water / methanol / 8 h / 50 °C
5.1: diphenyl phosphoryl azide; triethylamine / 20 h / Inert atmosphere
6.1: lithium aluminium tetrahydride / tetrahydrofuran / Cooling; Reflux
With
lithium aluminium tetrahydride; diphenyl phosphoryl azide; water; caesium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; cesium fluoride; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: caesium carbonate; cesium fluoride / N,N-dimethyl-formamide / 20 - 60 °C / Inert atmosphere
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / -5 - 0 °C
3.1: tetrahydrofuran / 18 h / Reflux
3.2: 24 h / Reflux
4.1: potassium hydroxide; water / methanol / 8 h / 50 °C
5.1: diphenyl phosphoryl azide; triethylamine / 20 h / Inert atmosphere
6.1: lithium aluminium tetrahydride / tetrahydrofuran / Cooling; Reflux
With
lithium aluminium tetrahydride; diphenyl phosphoryl azide; water; caesium carbonate; triethylamine; 3-chloro-benzenecarboperoxoic acid; cesium fluoride; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
