Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate

Base Information

• Chemical Name: Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate
• CAS No.: 112953-82-9
• Molecular Formula: C₂₀H₁₇ClO₆
• Molecular Weight: 388.804
• Mol file: 112953-82-9.mol

Synonyms:Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate

Chemical Property of Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate

There total 4 articles about Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-3,5-dimethoxybenzene (7051-16-3) → Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate (112953-82-9)

Guidance literature:

Multi-step reaction with 4 steps

1: AlCl₃

2: 1) NaH / 1) dioxane, 40 deg C, 2) 1 h, 160 deg C

3: 98.6 percent / AlCl₃ / benzene

4: 63 percent / K₂CO₃

With aluminium trichloride; sodium hydride; potassium carbonate; In benzene;

DOI:10.1248/cpb.39.2681

Reference yield:

(4-Methoxy-2-methylphenyl)acetyl chloride (726191-60-2) → Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate (112953-82-9)

Guidance literature:

Multi-step reaction with 4 steps

1: AlCl₃

2: 1) NaH / 1) dioxane, 40 deg C, 2) 1 h, 160 deg C

3: 98.6 percent / AlCl₃ / benzene

4: 63 percent / K₂CO₃

With aluminium trichloride; sodium hydride; potassium carbonate; In benzene;

DOI:10.1248/cpb.39.2681

Reference yield:

1-(2-Chloro-6-hydroxy-4-methoxy-phenyl)-2-(4-methoxy-2-methyl-phenyl)-ethanone → Ethyl <(5-chloro-3-(4-hydroxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate (112953-82-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) NaH / 1) dioxane, 40 deg C, 2) 1 h, 160 deg C

2: 98.6 percent / AlCl₃ / benzene

3: 63 percent / K₂CO₃

With aluminium trichloride; sodium hydride; potassium carbonate; In benzene;

DOI:10.1248/cpb.39.2681

upstream raw materials:

1-chloro-3,5-dimethoxybenzene

(4-Methoxy-2-methylphenyl)acetyl chloride

5-Chloro-7-methoxy-3-(4-methoxy-2-methyl-phenyl)-chromen-4-one

Downstream raw materials:

Ethyl <(3-(4-acetoxy-2-methylphenyl)-5-chloro-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate

[5-Chloro-3-(4-methoxy-2-methyl-phenyl)-4-oxo-4H-chromen-7-yloxy]-acetic acid

Ethyl <(5-chloro-3-(4-methoxy-2-methylphenyl)-4-oxo-4H-1-benzopyran-7-yl)oxy>acetate