N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

Base Information

Chemical Name:N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine
CAS No.:198646-94-5
Molecular Formula:C₂₅H₂₆N₄O₂
Molecular Weight:414.507
Hs Code.:

Synonyms:N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

Chemical Property:

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Technology Process of N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

There total 5 articles about N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(3-methylphenyl)-4-hydroxypiperidine hydrochloride

: 179026-35-8
1-(4-cyanophenylmethyl)-1H-imidazol-5-ylacetic acid

: 198646-94-5
N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

Guidance literature:: With 1,2-dichloro-ethane; triethylamine; trifluoroacetic acid; In water; N,N-dimethyl-formamide;

Reference yield:

: 198648-99-6
tert-butyl 4-hydroxy-4-(3-methylphenyl)-1-piperidinecarboxylate

: 198646-94-5
N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate

2: 1,2-dichloro-ethane; triethylamine; trifluoroacetic acid / water; N,N-dimethyl-formamide

With 1,2-dichloro-ethane; triethylamine; trifluoroacetic acid; In water; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 198646-94-5
N-{[1-(4-Cyanobenzyl)-1H-imidazol-5-yl]acetyl}-4-(3-methylphenyl)-4-hydroxy piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran

2: ethyl acetate

3: 1,2-dichloro-ethane; triethylamine; trifluoroacetic acid / water; N,N-dimethyl-formamide

With 1,2-dichloro-ethane; triethylamine; trifluoroacetic acid; In tetrahydrofuran; water; ethyl acetate; N,N-dimethyl-formamide;