Ethyl amino(2-phenylhydrazinylidene)acetate

Base Information

• Chemical Name: Ethyl amino(2-phenylhydrazinylidene)acetate
• CAS No.: 36999-43-6
• Molecular Formula: C10H13 N3 O2
• Molecular Weight: 207.232
• DSSTox Substance ID: DTXSID80694224
• Mol file: 36999-43-6.mol

Synonyms:36999-43-6;SCHEMBL9881210;DTXSID80694224;Ethyl amino(2-phenylhydrazinylidene)acetate

Chemical Property of Ethyl amino(2-phenylhydrazinylidene)acetate

Chemical Property:

• Vapor Pressure: 0.000186mmHg at 25°C
• Refractive Index: 1.558
• Boiling Point: 328.7°C at 760 mmHg
• Flash Point: 152.6°C
• PSA: 76.71000
• Density: 1.18g/cm³
• LogP: 1.70710
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 207.100776666
• Heavy Atom Count: 15
• Complexity: 235

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-amino-2-(2-phenylhydrazono)acetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(=NNC1=CC=CC=C1)N

Technology Process of Ethyl amino(2-phenylhydrazinylidene)acetate

There total 8 articles about Ethyl amino(2-phenylhydrazinylidene)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

ethyl chloro(2-phenylhydrazono)acetate (28663-68-5) → ethyl α-amino-α-(phenylhydrazono)glyoxylate (36999-43-6)

Guidance literature:

With ammonia; In 1,4-dioxane;

Reference yield: 73.0%

ethyl (phenylhydrazono)chloroacetate (28663-68-5) → ethyl 2-amino-2-(phenylhydrazono)acetate (1105634-63-6,36999-43-6)

Guidance literature:

With ammonia; In 1,4-dioxane; water; at 20 ℃; for 4h;

DOI:10.1021/acs.jmedchem.7b00457

Reference yield: 69.3%

ethyl (phenylhydrazono)chloroacetate (28663-68-5) → ethyl α-amino-α-(phenylhydrazono)glyoxylate (36999-43-6)

Guidance literature:

With ammonia; In 1,4-dioxane; at 20 ℃; for 8h;

DOI:10.1021/jo990687+

upstream raw materials:

N-phenylhydrazono α-bromoglyoxylate d'ethyle

ethyl (phenylhydrazono)chloroacetate

benzenediazonium sulphate

ethyl chloro(2-phenylhydrazono)acetate

Downstream raw materials:

ethyl 5-benzyl-1-phenyl-1H-1,2,4-triazole-3-carboxylate

bis(1H-3-ethoxycarbonyl-1-phenyl-1,2,4-triazol-5-yl)methane

1H-5-benzyl-3-carboxy-1-phenyl-1,2,4-triazole

bis(1H-3-carboxy-1-phenyl-1,2,4-triazol-5-yl)methane