Technology Process of C15H20FNO4
There total 8 articles about C15H20FNO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium hydroxide;
In
tetrahydrofuran; water;
at 0 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: copper(I) bromide dimethylsulfide complex; methylmagnesium bromide / tetrahydrofuran; dimethylsulfide; dibutyl ether / 0 - 20 °C / Inert atmosphere
2.1: di-n-butylboryl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.17 h / -78 °C / Inert atmosphere
2.2: 3 h / -78 - 0 °C / Inert atmosphere
3.1: sodium azide / dimethyl sulfoxide / 45 h / 20 °C / Inert atmosphere
4.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / Inert atmosphere
5.1: lithium hydroxide / tetrahydrofuran; water / 1 h / 0 °C / Inert atmosphere
With
sodium azide; copper(I) bromide dimethylsulfide complex; di-n-butylboryl trifluoromethanesulfonate; palladium 10% on activated carbon; methylmagnesium bromide; hydrogen; N-ethyl-N,N-diisopropylamine; lithium hydroxide;
In
tetrahydrofuran; dimethylsulfide; dichloromethane; dibutyl ether; water; dimethyl sulfoxide; ethyl acetate;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethyl acetate / Inert atmosphere
2: lithium hydroxide / tetrahydrofuran; water / 1 h / 0 °C / Inert atmosphere
With
palladium 10% on activated carbon; hydrogen; lithium hydroxide;
In
tetrahydrofuran; water; ethyl acetate;
DOI:10.1021/jm2007062
