Technology Process of 5-methyl-1-(4-pyridyl)-1H-1,2,3-benzotriazole
There total 1 articles about 5-methyl-1-(4-pyridyl)-1H-1,2,3-benzotriazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: phosphorus pentachloride; trichlorophosphate / 6 h / Reflux
2: N-ethyl-N,N-diisopropylamine / acetonitrile / 5 h / Reflux
3: sodium dithionite / ethanol; water / 3.5 h / Reflux
4: sodium nitrite; hydrogenchloride / water / 1 h / 0 - 25 °C
5: paraffin oil / 0.17 h / 360 - 370 °C / Inert atmosphere
6: nitric acid / 1 h / 85 - 90 °C
7: sodium dithionite / ethanol; water / 3.5 h / Reflux
8: sodium nitrite; hydrogenchloride / water / 1 h / 0 - 25 °C
With
hydrogenchloride; sodium dithionite; phosphorus pentachloride; nitric acid; N-ethyl-N,N-diisopropylamine; sodium nitrite; trichlorophosphate;
In
ethanol; water; acetonitrile; paraffin oil;
4: |Graebe-Ullmann Synthesis / 5: |Graebe-Ullmann Synthesis / 8: |Graebe-Ullmann Synthesis;
DOI:10.1007/s10593-012-1127-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: paraffin oil / 0.17 h / 340 - 350 °C / Inert atmosphere
2: nitric acid / 1 h / 85 - 90 °C
With
nitric acid;
In
paraffin oil;
1: |Graebe-Ullmann Synthesis;
DOI:10.1007/s10593-012-1127-7
- Guidance literature:
-
Multi-step reaction with 2 steps
1: paraffin oil / 0.17 h / 340 - 350 °C / Inert atmosphere
2: nitric acid / 1 h / 60 - 65 °C
With
nitric acid;
In
paraffin oil;
1: |Graebe-Ullmann Synthesis;
DOI:10.1007/s10593-012-1127-7
