3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran

Base Information

• Chemical Name: 3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran
• CAS No.: 223418-94-8
• Molecular Formula: C₂₅H₃₆O₃SSi
• Molecular Weight: 444.711
• Mol file: 223418-94-8.mol

Synonyms:3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran

Chemical Property of 3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran

There total 1 articles about 3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-trimethylsilyl-3-chloromethyl furane (94742-46-8) + β-cyclogeranyl p-tolyl sulfone → 3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran (223418-94-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; 1.) -78 deg C, 20 min, 2.) -78 deg C to room temperature, room temperature, 12 h;

DOI:10.1016/S0040-4020(98)01197-1

Reference yield: 93.0%

3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran (223418-94-8) → 3-<2-(2,6,6-trimethylcyclohex-1-enyl)ethyl>-2-trimethylsilylfuran (101822-26-8)

Guidance literature:

With methanol; disodium hydrogenphosphate; sodium amalgam; for 2h; Heating;

DOI:10.1016/S0040-4020(98)01197-1

Reference yield: 91.0%

3-<2-(2,6,6-trimethylcyclohex-1-enyl)-2-(p-toluenesulfonyl)ethyl>-2-trimethylsilylfuran (223418-94-8) → 5-Hydroxy-3-[2-(toluene-4-sulfonyl)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-ethyl]-5H-furan-2-one (204063-24-1)

Guidance literature:

With oxygen; 5,15,10,20-tetraphenylporphyrin; In dichloromethane; at -78 ℃; Irradiation;

DOI:10.1016/S0040-4020(98)01197-1

upstream raw materials:

2-trimethylsilyl-3-chloromethyl furane

Downstream raw materials:

3-<2-(2,6,6-trimethylcyclohex-1-enyl)ethyl>-2-trimethylsilylfuran

5-Hydroxy-3-[2-(toluene-4-sulfonyl)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-ethyl]-5H-furan-2-one

methyl (Z,E)-4-oxo-2-<2-(2,6,6-trimethylcyclohex-1-enyl)vinyl>but-2-enoate

5-Hydroxy-3-[2-(2,6,6-trimethyl-cyclohex-1-enyl)-ethyl]-5H-furan-2-one