1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone

Base Information

• Chemical Name: 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone
• CAS No.: 726180-37-6
• Molecular Formula: C₂₀H₂₄O₄
• Molecular Weight: 328.408
• Mol file: 726180-37-6.mol

Synonyms:1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone

Chemical Property of 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone

There total 3 articles about 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{2-[5-tert-butyl-2-(4-methoxy-benzyloxy)-phenyl]-oxiranyloxy}-trimethyl-silane → 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone (726180-37-6)

Guidance literature:

With hydrogenchloride; In diethyl ether; water; for 1h;

DOI:10.1021/jo049723h

Reference yield:

1-[5-tert-butyl-2-(4-methoxy-benzyloxy)-phenyl]-ethanone → 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone (726180-37-6)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / benzene

2: m-chloroperbenzoic acid / CH₂Cl₂ / -10 - 20 °C

3: 9.71 g / HCl / diethyl ether; H₂O / 1 h

With hydrogenchloride; triethylamine; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane; water; benzene;

DOI:10.1021/jo049723h

Reference yield:

{1-[5-tert-butyl-2-(4-methoxy-benzyloxy)-phenyl]-vinyloxy}-trimethyl-silane → 1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-hydroxyethanone (726180-37-6)

Guidance literature:

Multi-step reaction with 2 steps

1: m-chloroperbenzoic acid / CH₂Cl₂ / -10 - 20 °C

2: 9.71 g / HCl / diethyl ether; H₂O / 1 h

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane; water;

DOI:10.1021/jo049723h

Downstream raw materials:

1-[5-tert-butyl-2-(4-methoxybenzyloxy)-phenyl]-2-methoxymethoxyethanone

N-{1-[5-tert-butyl-2-(4-methoxybenzyloxy)phenyl]-2-methoxymethoxyvinyl}acetamide