3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester

Base Information

• Chemical Name: 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester
• CAS No.: 4311-01-7
• Molecular Formula: C₁₁H₁₄ClNO₂
• Molecular Weight: 227.691
• Mol file: 4311-01-7.mol

Synonyms:3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester

Chemical Property of 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester

There total 3 articles about 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(4-chlorophenyl)-2-cyanoacetate (147795-56-0,15032-43-6) → 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester (4311-01-7)

Guidance literature:

With sulfuric acid; hydrogen; platinum(IV) oxide; In acetic acid; under 37510.9 Torr; Ambient temperature;

DOI:10.1002/ardp.19683011006

Reference yield:

p-chlorobenzyl cyanide (140-53-4) → 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester (4311-01-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOEt

2: H₂, H₂SO₄ / PtO₂ / acetic acid / 37510.9 Torr / Ambient temperature

With sulfuric acid; hydrogen; sodium ethanolate; platinum(IV) oxide; In acetic acid;

DOI:10.1002/ardp.19683011006

Reference yield:

→ 3-Amino-2-<4-chlor-phenyl>-propionsaeureaethylester (4311-01-7)

Guidance literature:

Ethyl-4-chlorphenylcyanacetat, H2/Pd-C, wss.-ethanol. HCl, Druck;

DOI:10.1021/jo01068a101

upstream raw materials:

ethyl 2-(4-chlorophenyl)-2-cyanoacetate

p-chlorobenzyl cyanide

Downstream raw materials:

3-Amino-2-(4-chlor-phenyl)-propanol-⁽¹⁾

1-chloro-4-(2-chloro-1-isothiocyanatomethyl-ethyl)-benzene

3-Chloro-2-(4-chloro-phenyl)-propylamine