5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride

Base Information

• Chemical Name: 5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride
• CAS No.: 1049798-88-0
• Molecular Formula: C₁₄H₈Cl₂F₃N₃*ClH
• Molecular Weight: 382.6

Synonyms:5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride

Chemical Property of 5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride

Chemical Property:

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Technology Process of 5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride

There total 1 articles about 5⁽⁶⁾-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

(2-chloro-5-trifluoromethylphenyl)isothiocyanate (23165-49-3) + 4-Chloro-1,2-phenylenediamine (95-83-0) → 5(6)-chloro-2-(2-chloro-5-trifluoromethylanilino)-1H-benzimidazole hydrochloride (1049798-88-0)

Guidance literature:

(2-chloro-5-trifluoromethylphenyl)isothiocyanate; 4-Chloro-1,2-phenylenediamine; With Celite; N-ethyl-N,N-diisopropylamine; copper(l) chloride; In toluene; acetonitrile; at 80 ℃; for 1h;

With hydrogenchloride; In ethanol; Further stages.;

DOI:10.1016/j.ejmech.2007.10.009

upstream raw materials:

(2-chloro-5-trifluoromethylphenyl)isothiocyanate

4-Chloro-1,2-phenylenediamine

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