methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

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Chemical Name:methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate
CAS No.:887243-06-3
Molecular Formula:C₃₁H₃₃F₂N₃O₄
Molecular Weight:549.618
Hs Code.:

Synonyms:methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

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Chemical Property of methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

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Technology Process of methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

There total 1 articles about methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 887242-67-3
methyl (2S)-({[4-chloro-2-({[(2,6-dimethylphenyl)amino]carbonyl}amino)phenyl]carbonyl}amino)(cyclohexyl)-ethanoate

: 168267-41-2
(3,4-difluorophenyl)boronic acid

: 887243-06-3
methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

Guidance literature:: With sodium carbonate; (bis(tricyclohexyl)phosphine)palladium(II) dichloride; In water; acetonitrile; at 150 ℃; for 0.0833333h; Irradiation;

Reference yield: 29.0%

: 887243-06-3
methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate

: (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoic acid

Guidance literature:: methyl (2S)-cyclohexyl-({[3-({[(2,6-dimethylphenyl)amino]carbonyl}amino)-3',4'-difluoro-4-biphenylyl]carbonyl}amino)ethanoate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; In water;