2-(4-methoxyphenyl)-1-phenyl-1H-imidazole

Base Information

• Chemical Name: 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole
• CAS No.: 852525-28-1
• Molecular Formula: C₁₆H₁₄N₂O
• Molecular Weight: 250.3
• Mol file: 852525-28-1.mol

Synonyms:2-(4-methoxyphenyl)-1-phenyl-1H-imidazole

Chemical Property of 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole

There total 5 articles about 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-phenylimidazole (7164-98-9) + para-iodoanisole (696-62-8) → 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole (852525-28-1)

Guidance literature:

With copper(l) iodide; palladium on activated charcoal; In N,N-dimethyl-formamide; at 140 ℃; for 144h;

DOI:10.1016/j.tet.2006.12.068

Reference yield: 62.0%

1-phenylimidazole (7164-98-9) + para-iodoanisole (696-62-8) → 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole (852525-28-1) + 5-(4-methoxyphenyl)-1-phenyl-1H-imidazole (852525-27-0) + 2,5-bis(4-methoxyphenyl)-1-phenyl-1H-imidazole

Guidance literature:

With copper(l) iodide; cesium fluoride; palladium diacetate; In N,N-dimethyl-formamide; at 140 ℃; for 48h;

DOI:10.1002/ejoc.200500636

Reference yield: 49.0%

1-phenylimidazole (7164-98-9) + para-iodoanisole (696-62-8) → 2-(4-methoxyphenyl)-1-phenyl-1H-imidazole (852525-28-1) + 5-(4-methoxyphenyl)-1-phenyl-1H-imidazole (852525-27-0)

Guidance literature:

With triphenyl-arsane; cesium fluoride; palladium diacetate; In N,N-dimethyl-formamide; at 140 ℃; for 42h;

DOI:10.1021/jo050274a

upstream raw materials:

1-phenylimidazole

1-bromo-4-methoxy-benzene

para-iodoanisole

Downstream raw materials:

1-(4-methoxyphenyl)-4,5-diphenylimidazo[1,5-a]quinoline