(1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal

Base Information

• Chemical Name: (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal
• CAS No.: 688359-70-8
• Molecular Formula: C₁₉H₂₇NO₃
• Molecular Weight: 317.428

Synonyms:(1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal

Chemical Property of (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal

There total 2 articles about (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(R)-1-phenyl-ethyl-amine (3886-69-9) + C11H16O3 (688359-69-5) → (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal (688359-70-8)

Guidance literature:

In ethanol; Heating;

DOI:10.1016/j.tetasy.2003.11.040

Reference yield:

hexahydro-4’H-spiro[1,3-dioxolane-2,1’-pentalen]-4’-one → (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal (688359-70-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / KOH / acetonitrile; H₂O / 60 °C

2: 89 percent / ethanol / Heating

With potassium hydroxide; In ethanol; water; acetonitrile;

DOI:10.1016/j.tetasy.2003.11.040

Reference yield: 100.0%

(1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal (688359-70-8) → (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one

Guidance literature:

With hydrogenchloride; In acetone; at 20 ℃; for 5h;

DOI:10.1016/j.tetasy.2003.11.040

upstream raw materials:

(R)-1-phenyl-ethyl-amine

C₁₁H₁₆O₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 688359-70-8 (1S,5S,6S,1'R)-6-hydroxy-6-(1-phenylethyl-aminomethyl)-bicyclo[3.3.0]octan-2-one ethylene ketal

Send

Send

Metric Ton KG G Pound L ML

Send

Send