C₂₆H₂₉N₃

Base Information

• Chemical Name: C₂₆H₂₉N₃
• CAS No.: 1236078-13-9
• Molecular Formula: C₂₆H₂₉N₃
• Molecular Weight: 383.536
• Mol file: 1236078-13-9.mol

Synonyms:C₂₆H₂₉N₃

Chemical Property of C₂₆H₂₉N₃

Chemical Property:

Purity/Quality:

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Technology Process of C₂₆H₂₉N₃

There total 1 articles about C₂₆H₂₉N₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine (90213-66-4) + p-tert-butylphenylboronic acid (123324-71-0) → C26H29N3 (1236078-13-9)

Guidance literature:

With potassium phosphate; palladium diacetate; CyJohnPhos; In 1,4-dioxane; for 0.25h; Inert atmosphere; Heating;

DOI:10.1016/j.tetlet.2010.05.093

Reference yield: 83.0%

C26H29N3 (1236078-13-9) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → 2,4-bis(4-tert-butylphenyl)-10H-pyrimido[5',4':4,5]pyrrolo[2,1-a]isoindole

Guidance literature:

C₂₆H₂₉N₃; 1-Bromo-2-bromomethyl-benzene; With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; In N,N-dimethyl acetamide; at 60 ℃; for 3h; Inert atmosphere;

With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid; In N,N-dimethyl acetamide; at 130 ℃; for 4h; regioselective reaction; Inert atmosphere;

DOI:10.1055/s-0036-1588734

Reference yield: 58.0%

2-bromo-5-methoxybenzyl bromide (19614-12-1) + C26H29N3 (1236078-13-9) → 2,4-bis(4-tert-butylphenyl)-8-methoxy-10H-pyrimido[5',4':4,5]pyrrolo[2,1-a]isoindole

Guidance literature:

2-bromo-5-methoxybenzyl bromide; C₂₆H₂₉N₃; With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; In N,N-dimethyl acetamide; at 60 ℃; for 3h; Inert atmosphere;

With palladium diacetate; potassium carbonate; tricyclohexylphosphine tetrafluoroborate; Trimethylacetic acid; In N,N-dimethyl acetamide; at 130 ℃; for 4h; regioselective reaction; Inert atmosphere;

DOI:10.1055/s-0036-1588734

upstream raw materials:

2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine

p-tert-butylphenylboronic acid