1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol

Base Information

• Chemical Name: 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol
• CAS No.: 1073632-86-6
• Molecular Formula: C₁₅H₁₄F₁₀O
• Molecular Weight: 400.26
• Mol file: 1073632-86-6.mol

Synonyms:1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol

Chemical Property of 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol

There total 10 articles about 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Pentafluoroethyl iodide (354-64-3) + 5-phenyl-n-valeric acid methyl ester (20620-59-1) → 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol (1073632-86-6)

Guidance literature:

Pentafluoroethyl iodide; 5-phenyl-n-valeric acid methyl ester; With methyllithium lithium bromide; In diethyl ether; at -78 ℃; for 4h;

With potassium hydrogensulfate; In diethyl ether; water; pH=5.0;

DOI:10.1021/jo801469x

Reference yield: 88.0%

Pentafluoroethyl iodide (354-64-3) + 5-phenyl-pentanoic acid pentafluorophenyl ester (1073632-57-1) → 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol (1073632-86-6)

Guidance literature:

Pentafluoroethyl iodide; 5-phenyl-pentanoic acid pentafluorophenyl ester; With methyllithium lithium bromide; In diethyl ether; at -78 ℃; for 1.5h;

With potassium hydrogensulfate; In diethyl ether; water; pH=5.0;

DOI:10.1021/jo801469x

Reference yield: 84.0%

Pentafluoroethyl iodide (354-64-3) + 1-(morpholin-4-yl)-5-phenylpentan-1-one (1071001-86-9) → 1,1,1,2,2-pentafluoro-7-phenyl-heptan-3-one (1071000-98-0) + 1,1,1,2,2-pentafluoro-3-pentafluoroethyl-7-phenyl-heptan-3-ol (1073632-86-6)

Guidance literature:

Pentafluoroethyl iodide; 1-(morpholin-4-yl)-5-phenylpentan-1-one; With methyllithium lithium bromide; In diethyl ether; at -78 ℃; for 2h;

With potassium hydrogensulfate; In diethyl ether; water; pH=5.0;

DOI:10.1021/jo801469x

upstream raw materials:

Pentafluoroethyl iodide

1-(morpholin-4-yl)-5-phenylpentan-1-one

5-phenyl-pentanoic acid pentafluorophenyl ester

5-phenyl-pentanoyl fluoride