4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)-

Base Information

Chemical Name:4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)-
CAS No.:280745-36-0
Molecular Formula:C25H31 N O4
Molecular Weight:409.52
Hs Code.:

Synonyms:4H-Bis[1,3]dioxolo[4,5-c:4',5'-e]azepine,5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)- (9CI)

Suppliers and Price of 4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)-

Chemical Property:

PSA：40.16000
LogP:4.06970

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)-

There total 2 articles about 4H-Bis1,3dioxolo4,5-c:4,5-eazepine, 5-(diphenylmethyl)hexahydro-2,2,8,8-tetramethyl-, (3aR,6aR,9aR,9bR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 91-00-9
Benzhydrylamine

: 280745-35-9
2,3:4,5-Di-O-isopropylidene-D-manno-hexodialdose

: 280745-36-0
(3R,4R,5R,6R)-N-Benzhydryl-3,4:5,6-bis(isopropylidenedioxy)azepane

Guidance literature:: With 3 A molecular sieve; sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃; for 15h;
DOI:10.1039/a908986a

Reference yield:

: 40617-60-5
1,2:5,6-bis-O-(1-methylethylidene)-D-chiro-inositol

: 280745-36-0
(3R,4R,5R,6R)-N-Benzhydryl-3,4:5,6-bis(isopropylidenedioxy)azepane

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / NaIO₄; silica / CH₂Cl₂ / 1.33 h / 20 °C

2: 71 percent / NaCNBH₃; molecular sieves 3 Angstroem; AcOH / methanol / 15 h / 20 °C

With sodium periodate; 3 A molecular sieve; silica gel; sodium cyanoborohydride; acetic acid; In methanol; dichloromethane; 1: Oxidation / 2: Cyclization;
DOI:10.1039/a908986a