tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate

Base Information

Chemical Name:tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate
CAS No.:1035351-21-3
Molecular Formula:C₂₃H₃₃FO₇P₂
Molecular Weight:502.457
Hs Code.:

Synonyms:tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate

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Technology Process of tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate

There total 1 articles about tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1035351-19-9
tetraethyl 4,5-dimethylbenzene-1,2-diphosphonate

: 459-57-4
4-fluorobenzaldehyde

: 1035351-21-3
tetraethyl 4-methyl-5-[2-(4-fluorophenyl)-2-hydroxyethyl]benzene-1,2-diphosphonate

Guidance literature:: tetraethyl 4,5-dimethylbenzene-1,2-diphosphonate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -70 ℃; for 0.5h;

4-fluorobenzaldehyde; In tetrahydrofuran; hexane; at -70 ℃; for 2h; Further stages.;
DOI:10.1016/j.tet.2008.03.020