(S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

Base Information

Chemical Name:(S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester
CAS No.:925681-77-2
Molecular Formula:C₃₃H₃₂O₃
Molecular Weight:476.615
Hs Code.:

Synonyms:(S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

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Technology Process of (S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

There total 2 articles about (S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 2510-77-2
α-benzoyldiphenylmethyl chloride

: 51146-56-6,58560-75-1
(S)-ibuprofen

: 925681-77-2
(S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

Guidance literature:: With silver tetrafluoroborate; silver carbonate; In dichloromethane; at -60 - 0 ℃;
DOI:10.1016/j.tet.2006.11.015

Reference yield:

: 4237-46-1
α-phenylbenzoin

: 925681-77-2
(S)-4-isobutyl-α-methylphenylacetic acid 2-oxo-1,2,2-triphenylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / pyridine; thionyl chloride / 0 °C

2: 64 percent / silver(I) carbonate; silver(I) tetrafluoroborate / CH₂Cl₂ / -60 - 0 °C

With pyridine; silver tetrafluoroborate; thionyl chloride; silver carbonate; In dichloromethane;
DOI:10.1016/j.tet.2006.11.015