methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Base Information

Chemical Name:methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate
CAS No.:1219452-45-5
Molecular Formula:C₁₃H₁₁Cl₂FO₂
Molecular Weight:289.134
Hs Code.:
DSSTox Substance ID:DTXSID20705000
Wikidata:Q82637628

Synonyms:DTXSID20705000;1219452-45-5;methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Suppliers and Price of methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:288.0120131
Heavy Atom Count:18
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C(=CC=C(C1=CC=C(C=C1)F)Cl)CCl
Isomeric SMILES:COC(=O)/C(=C/C=C(/C1=CC=C(C=C1)F)\Cl)/CCl

Technology Process of methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

There total 2 articles about methyl (2Z,4Z)-5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1219452-55-7
(Z)-methyl 5-chloro-5-(4-fluorophenyl)-3-hydroxy-2-methylenepent-4-enoate

: 1219452-45-5
(2Z,4Z)-methyl 5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Guidance literature:: With bis(trichloromethyl) carbonate; triethylamine; Triphenylphosphine oxide; In dichloromethane; at 0 - 20 ℃; stereoselective reaction;
DOI:10.2174/157017810791112469

Reference yield: 46.0%

: 1219452-55-7
(Z)-methyl 5-chloro-5-(4-fluorophenyl)-3-hydroxy-2-methylenepent-4-enoate

: 1242066-47-2
(2E,4Z)-methyl 5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

: 1219452-45-5
(2Z,4Z)-methyl 5-chloro-2-(chloromethyl)-5-(4-fluorophenyl)penta-2,4-dienoate

Guidance literature:: With bis(trichloromethyl) carbonate; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;
DOI:10.2174/157017810791112469