Technology Process of (E)-methyl 3-(3,6,6-trimethylcyclohex-1-enyl)acrylate
There total 5 articles about (E)-methyl 3-(3,6,6-trimethylcyclohex-1-enyl)acrylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-methyl 3-(1-hydroxy-2,2,5-trimethylcyclohexyl)acrylate;
With
Martins sulfurane;
In
tetrachloromethane;
at 0 - 20 ℃;
for 1.5h;
Inert atmosphere;
With
water;
In
tetrachloromethane;
for 0.333333h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen / palladium on activated charcoal / methanol / 25 °C
2.1: lithium diisopropyl amide / tetrahydrofuran; diethyl ether / 1 h / -78 °C
2.2: 1 h / -78 °C
3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran / 1 h / -72 °C / Inert atmosphere
4.1: Martins sulfurane / tetrachloromethane / 1.5 h / 0 - 20 °C / Inert atmosphere
4.2: 0.33 h
With
Martins sulfurane; hydrogen; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; tetrachloromethane; diethyl ether;
- Guidance literature:
-
Multi-step reaction with 6 steps
3.1: hydrogen / palladium on activated charcoal / methanol / 25 °C
4.1: lithium diisopropyl amide / tetrahydrofuran; diethyl ether / 1 h / -78 °C
4.2: 1 h / -78 °C
5.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran / 1 h / -72 °C / Inert atmosphere
6.1: Martins sulfurane / tetrachloromethane / 1.5 h / 0 - 20 °C / Inert atmosphere
6.2: 0.33 h
With
Martins sulfurane; hydrogen; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; tetrachloromethane; diethyl ether;
