C₁₅H₁₈O₅

Base Information

• Chemical Name: C₁₅H₁₈O₅
• CAS No.: 1280213-79-7
• Molecular Formula: C₁₅H₁₈O₅
• Molecular Weight: 278.305
• Mol file: 1280213-79-7.mol

Synonyms:C₁₅H₁₈O₅

Chemical Property of C₁₅H₁₈O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₈O₅

There total 10 articles about C₁₅H₁₈O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C17H22O5 (1280213-76-4) → C15H18O5 (1280213-79-7)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 12h; diastereoselective reaction;

DOI:10.1016/j.tetlet.2011.01.078

Reference yield: 10.0%

C17H22O5 (1280213-76-4) → C15H18O5 (1280213-79-7) + C15H18O5 + C15H18O5 (1280213-77-5)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 11h; optical yield given as %de; diastereoselective reaction;

DOI:10.1016/j.tetlet.2011.01.078

Reference yield:

(R)-6-Benzyloxymethyl-5,6-dihydro-2-pyrone (120996-46-5) → C15H18O5 (1280213-79-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dihydrogen peroxide; sodium hydroxide / methanol; water / 0.02 h / 0 °C

2.1: diisobutylaluminium hydride / toluene / 1 h / -78 °C

2.2: 1 h / -40 °C

3.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 12 h / 20 °C

With lithium hydroxide monohydrate; dihydrogen peroxide; diisobutylaluminium hydride; sodium hydroxide; In tetrahydrofuran; methanol; water; toluene; 2.2: Horner-Wadsworth-Emmons olefination / 3.1: intramolecular oxy-Michael reaction;

DOI:10.1016/j.tetlet.2011.01.078

upstream raw materials:

Acrylic acid (R)-1-benzyloxymethyl-but-3-enyl ester

C₁₇H₂₂O₅

(R)-6-Benzyloxymethyl-5,6-dihydro-2-pyrone

(1S,4R,6S)-4-Benzyloxymethyl-3,7-dioxa-bicyclo[4.1.0]heptan-2-one

Downstream raw materials:

C₁₅H₂₀O₄

C₂₁H₃₄O₄Si

C₃₆H₅₆O₄Si₂