ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate

Base Information

• Chemical Name: ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate
• CAS No.: 143887-01-8
• Molecular Formula: C₁₆H₁₉N₇O₄
• Molecular Weight: 373.371
• Mol file: 143887-01-8.mol

Synonyms:ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate

Chemical Property of ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate

There total 2 articles about ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate (6506-86-1) + N-benzimidoyl-N-methyl-hydrazine hydrochloride (144154-87-0) → ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate (143887-01-8)

Guidance literature:

With triethylamine; In isopropyl alcohol; for 4h; Heating;

DOI:10.1021/jm00098a014

Reference yield:

methyl benzimidate hydrochloride (5873-90-5) → ethyl <6-amino-4-(2-benzimidoyl-2-methylhydrazino)-5-nitropyridin-2-yl>carbamate (143887-01-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / 2 h / Ambient temperature

2: 86 percent / Et₃N / propan-2-ol / 4 h / Heating

With triethylamine; In methanol; isopropyl alcohol;

DOI:10.1021/jm00098a014

upstream raw materials:

ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

N-benzimidoyl-N-methyl-hydrazine hydrochloride

methyl benzimidate hydrochloride