C₂₅H₂₁F₃N₂O₃

Base Information

Chemical Name:C₂₅H₂₁F₃N₂O₃
CAS No.:1329988-97-7
Molecular Formula:C₂₅H₂₁F₃N₂O₃
Molecular Weight:454.449
Hs Code.:

C<sub>25</sub>H<sub>21</sub>F<sub>3</sub>N<sub>2</sub>O<sub>3</sub>

Synonyms:C₂₅H₂₁F₃N₂O₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₅H₂₁F₃N₂O₃

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Technology Process of C₂₅H₂₁F₃N₂O₃

There total 7 articles about C₂₅H₂₁F₃N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1329991-28-7
C₃₁H₃₅F₃N₂O₃Si

: 1329988-97-7
C₂₅H₂₁F₃N₂O₃

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 16.1667h;

Reference yield:

: 15852-73-0
(3-Bromophenyl)methanol

: 1329988-97-7
C₂₅H₂₁F₃N₂O₃

Guidance literature:: Multi-step reaction with 3 steps

1: 1H-imidazole / dichloromethane / 1 h / 20 °C

2: potassium phosphate / tri-tert-butyl phosphine; bis(tri-t-butylphosphine)palladium⁽⁰⁾ / tetrahydrofuran / 32 h / 80 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 16.17 h / 0 - 20 °C

With 1H-imidazole; potassium phosphate; tetrabutyl ammonium fluoride; acetic acid; bis(tri-t-butylphosphine)palladium⁽⁰⁾; tri-tert-butyl phosphine; In tetrahydrofuran; dichloromethane;

Reference yield:

: 30377-63-0
N-ethyl-4-(trifluoromethyl)benzene-1,2-diamine

: 1329988-97-7
C₂₅H₂₁F₃N₂O₃

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran / 1.17 h / 20 °C / Inert atmosphere

2: pyridine / copper diacetate / dichloromethane / 8 h / 50 °C

3: potassium phosphate / tri-tert-butyl phosphine; bis(tri-t-butylphosphine)palladium⁽⁰⁾ / tetrahydrofuran / 32 h / 80 °C / Inert atmosphere

4: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 16.17 h / 0 - 20 °C

With pyridine; potassium phosphate; tetrabutyl ammonium fluoride; acetic acid; bis(tri-t-butylphosphine)palladium⁽⁰⁾; tri-tert-butyl phosphine; copper diacetate; In tetrahydrofuran; dichloromethane;