1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

Base Information

Chemical Name:1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione
CAS No.:1600516-61-7
Molecular Formula:C₂₅H₁₃F₃N₂O₄
Molecular Weight:462.384
Hs Code.:

Synonyms:1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

Suppliers and Price of 1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

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Technology Process of 1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

There total 1 articles about 1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 178697-87-5
(E)-2-(4-(trifluoromethyl)benzylidene)-1H-indene-1,3(2H)-dione

: 1875-48-5
N-aminophthalamide

: 1600516-61-7
1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

Guidance literature:: With lead(IV) tetraacetate; potassium carbonate; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2014.03.014

Reference yield:

: 941-69-5
N-phenyl-maleimide

: 1600516-61-7
1-phthalimido-3-(4-trifluoromethylphenyl)spiro[aziridine-2,2’-indene]-1’,3’-dione

: rac-(3'R,3a'R,6a'S)-5'-phenyl-2'-phthalimido-3'-[4-(trifluoromethyl)phenyl]-3a',6a'-dihydro-2'H-spiro[indene-2,1'-pyrrolo[3,4-c]pyrrole]-1,3,4',6'(3'H,5'H)-tetrone

: rac-(3'R,3a'S,6a'R)-5'-phenyl-2'-phthalimido-3'-[4-(trifluoromethyl)phenyl]-3a',6a'-dihydro-2'H-spiro[indene-2,1'-pyrrolo[3,4-c]pyrrole]-1,3,4',6'(3'H,5'H)-tetrone

Guidance literature:: In benzene; at 75 ℃; for 8h; Overall yield = 79 %; Overall yield = 250 mg; Optical yield = 78.571 %de;
DOI:10.1016/j.tetlet.2014.03.014