Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Base Information

Chemical Name:Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate
CAS No.:85453-58-3
Molecular Formula:C₃₉H₆₇NO₇SSi₂
Molecular Weight:750.2
Hs Code.:

Synonyms:Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Suppliers and Price of Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

There total 4 articles about Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 77494-47-4
Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(methylamino)-8-(phenylsulfonyl)-5,13-prostadienoate

: 85453-59-4
Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(E-methylnitrono)-8-(phenylsulfonyl)-5,13-prostadienoate

: 85453-58-3
Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Guidance literature:: With peracetic acid; sodium tungstate; sodium carbonate; In methanol; water; at 25 ℃; for 10h;
DOI:10.1021/jo00161a010

Reference yield: 8.0%

: 77494-47-4
Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(methylamino)-8-(phenylsulfonyl)-5,13-prostadienoate

: 85453-57-2
Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(methylhydroxyamino)-8-(phenylsulfonyl)-5,13-prostadienoate

: 85453-58-3
Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Guidance literature:: With dihydrogen peroxide; potassium carbonate; In methanol; water; acetonitrile; at 0 ℃; for 5h;
DOI:10.1021/jo00161a010

Reference yield:

: 77506-98-0
Methyl (5Z,13E,8R,9S,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(dimethylamino)-8-(phenylsulfonyl)-5,13-prostadienoate

: 85453-58-3
Methyl (5Z,13E,8R,11R,12S,15S)-11,15-Bis(tert-butyldimethylsiloxy)-9-(anti-oximino)-8-(phenylsulfonyl)-5,13-prostadienoate

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / sodium bicarbonate / CH₂Cl₂ / 72 h / 30 °C

2: 92 percent / zinc powder / tetrahydrofuran / 3 h / Heating

3: 8 percent / 30percent H₂O₂, Potassium carbonate / methanol; acetonitrile; H₂O / 5 h / 0 °C

With dihydrogen peroxide; sodium hydrogencarbonate; potassium carbonate; zinc; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/jo00161a010