N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate

Base Information

• Chemical Name: N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate
• CAS No.: 1370047-96-3
• Molecular Formula: C₁₆H₂₀N₂O₂*H₂O₄S
• Molecular Weight: 370.426
• Mol file: 1370047-96-3.mol

Synonyms:N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate

Chemical Property of N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate

There total 3 articles about N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide (1370047-83-8) → N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate (1370047-96-3)

Guidance literature:

With sulfuric acid; In ethanol; water; at 20 ℃; for 0.166667h;

DOI:10.1007/s00706-011-0615-2

Reference yield:

3-Hydroxy-3-methyl-2-butanone (115-22-0) → N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate (1370047-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methylate / methanol / 5 h / 35 - 40 °C

2: sulfuric acid / ethanol; water / 0.17 h / 20 °C

With sulfuric acid; sodium methylate; In methanol; ethanol; water;

DOI:10.1007/s00706-011-0615-2

Reference yield:

N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrochloride (1370047-91-8) → N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrogensulfate (1370047-96-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; sodium hydroxide / water / pH 7 - 8

2: sulfuric acid / ethanol; water / 0.17 h / 20 °C

With sulfuric acid; potassium carbonate; sodium hydroxide; In ethanol; water;

DOI:10.1007/s00706-011-0615-2

upstream raw materials:

N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide

N-(2,4-dimethylphenyl)-2,5-dihydro-2-imino-4,5,5-trimethylfuran-3-carboxamide hydrochloride

3-Hydroxy-3-methyl-2-butanone

Downstream raw materials:

N-(2,4-dimethylphenyl)-2,5-dihydro-4,5,5-trimethyl-2-oxofuran-3-carboxamide