Technology Process of C63H89NO15
There total 10 articles about C63H89NO15 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate;
In
dichloromethane;
at 20 ℃;
DOI:10.1021/ja062740z
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 301 mg / NaHCO3 / dioxane; aq. NaHCO3
2: 77 percent / AW300; TMSOTf / diethyl ether; tetrahydrofuran / 1 h / -30 °C
3: H2 / Pd/C / ethyl acetate; ethanol
4: pyridine; DMAP / 20 °C
5: TFA / CH2Cl2 / 0 - 20 °C
6: 67 percent / HBTu; NMM / CH2Cl2 / 20 °C
With
4-methyl-morpholine; pyridine; dmap; trimethylsilyl trifluoromethanesulfonate; hydrogen; sodium hydrogencarbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; trifluoroacetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; ethanol; dichloromethane; sodium hydrogencarbonate; ethyl acetate;
DOI:10.1021/ja062740z
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 77 percent / AW300; TMSOTf / diethyl ether; tetrahydrofuran / 1 h / -30 °C
2: H2 / Pd/C / ethyl acetate; ethanol
3: pyridine; DMAP / 20 °C
4: TFA / CH2Cl2 / 0 - 20 °C
5: 67 percent / HBTu; NMM / CH2Cl2 / 20 °C
With
4-methyl-morpholine; pyridine; dmap; trimethylsilyl trifluoromethanesulfonate; hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; trifluoroacetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; ethyl acetate;
DOI:10.1021/ja062740z
