Pyrimido[1,2-a]benzimidazol-4-ol

Base Information

Chemical Name:Pyrimido[1,2-a]benzimidazol-4-ol
CAS No.:36320-82-8
Molecular Formula:C₁₀H₇N₃O
Molecular Weight:185.185
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40605013
Wikidata:Q82503115
Mol file:36320-82-8.mol

Synonyms:pyrimido[1,2-a]benzimidazol-4-ol;36320-82-8;1087654-58-7;10H-pyrimido[1,2-a]benzimidazol-4-one;Pyrimido[1,2-a]benzimidazol-4(1H)-one (9CI);Benzo[4,5]imidazo[1,2-a]pyrimidin-4(1H)-one;Benzo[4,5]imidazo[1,2-a]pyrimidin-4-ol;Pyrimido[1,2-a]benzimidazol-4(10H)-one;SCHEMBL1698064;DTXSID40605013;JQKQZINMXYVXAF-UHFFFAOYSA-N;pyrimido[1,2-a]benzimidazol-4-one;MFCD11855748;STK499439;AKOS002681538;LS-09466;Pyrimido[1,2-a]benzimidazol-4(1H)-one;pyrimido[1,2-a][1,3]benzimidazol-4-ol;CS-0325293;1,8,10-triazatricyclo[7.4.0.0?,?]trideca-2,4,6,8,11-pentaen-13-one;1,8,10-TRIAZATRICYCLO[7.4.0.0(2),?]TRIDECA-2,4,6,8,10,12-HEXAEN-13-OL;1,8,10-triazatricyclo[7.4.0.0?,?]trideca-2,4,6,8,10,12-hexaen-13-ol;1,8,10-Triazatricyclo[7.4.0.0{2,7}]trideca-2(7),3,5,8,10,12-hexaen-13-ol

Suppliers and Price of Pyrimido[1,2-a]benzimidazol-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
Pyrimido[1,2-a]benzimidazol-4(10H)-one 97.00%
25G
$ 3410.00

AccelPharmtech
Pyrimido[1,2-a]benzimidazol-4(10H)-one 97.00%
5G
$ 2010.00

AccelPharmtech
Pyrimido[1,2-a]benzimidazol-4(10H)-one 97.00%
2G
$ 940.00

AccelPharmtech
Pyrimido[1,2-a]benzimidazol-4(10H)-one 97.00%
1G
$ 570.00

Total 4 raw suppliers

Chemical Property of Pyrimido[1,2-a]benzimidazol-4-ol

Chemical Property:

Boiling Point:351.4±25.0 °C(Predicted)
PKA:1.34±0.20(Predicted)
PSA：50.16000
Density:1.47±0.1 g/cm3(Predicted)
LogP:1.17580
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:185.058911855
Heavy Atom Count:14
Complexity:334

Purity/Quality:

99% ^*data from raw suppliers

Pyrimido[1,2-a]benzimidazol-4(10H)-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC3=NC=CC(=O)N23

Technology Process of Pyrimido[1,2-a]benzimidazol-4-ol

There total 4 articles about Pyrimido[1,2-a]benzimidazol-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 4-oxo-4,10-dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-3-carboxylic acid

: 36320-82-8
benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-one

Guidance literature:: With copper; In quinoline; at 200 ℃; for 1h;

Reference yield:

: 40519-93-5
ethyl 4-oxo-4,10-dihydrobenzo[4,5]imidazo [1,2-a]pyrimidine-3-carboxylate

: 36320-82-8
benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / 2.5 h / 85 °C

2: copper / quinoline / 1 h / 200 °C

With water; copper; sodium hydroxide; In quinoline;

Reference yield:

: 934-32-7
1H-benzimidazol-2-amine

: 36320-82-8
benzo[4,5]imidazo[1,2-a]pyrimidin-4(10H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: methanol / 5 h / Reflux

2: sodium hydroxide; water / 2.5 h / 85 °C

3: copper / quinoline / 1 h / 200 °C

With water; copper; sodium hydroxide; In quinoline; methanol;