C₁₄H₁₂N₄O

Base Information

• Chemical Name: C₁₄H₁₂N₄O
• CAS No.: 565178-04-3
• Molecular Formula: C₁₄H₁₂N₄O
• Molecular Weight: 252.275
• Mol file: 565178-04-3.mol

Synonyms:C₁₄H₁₂N₄O

Chemical Property of C₁₄H₁₂N₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₂N₄O

There total 1 articles about C₁₄H₁₂N₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Δ2,α-Pyrrolidinemalononitrile (5626-75-5) + phenyl isocyanate (103-71-9) → C14H12N4O (565178-04-3)

Guidance literature:

In dichloromethane;

DOI:10.1016/j.ejmech.2012.06.048

Reference yield: 90.0%

C14H12N4O (565178-04-3) + dimethyl sulfate (77-78-1) → (E/Z)-3-methylimino-1-oxo-2-phenyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile (1198113-56-2)

Guidance literature:

C₁₄H₁₂N₄O; dimethyl sulfate; In benzene; for 3h; Reflux;

With sodium hydroxide; In water;

DOI:10.1016/j.ejmech.2009.06.028

Reference yield: 51.0%

C14H12N4O (565178-04-3) + 4-fluorobenzonitrile (1194-02-1,143234-87-1) → (E/Z)-3-(4-cyanophenyl)imino-1-oxo-2-phenyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile (1198113-77-7)

Guidance literature:

C₁₄H₁₂N₄O; With sodium hydride; In hexane; N,N-dimethyl-formamide; mineral oil; at 80 ℃; for 1h;

4-fluorobenzonitrile; In hexane; N,N-dimethyl-formamide; mineral oil; for 6h; Heating;

DOI:10.1016/j.ejmech.2009.06.028

upstream raw materials:

Δ^2,α-Pyrrolidinemalononitrile

phenyl isocyanate

Downstream raw materials:

(E/Z)-3-butylimino-1-oxo-2-phenyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile

(E/Z)-3-(4-cyanophenyl)imino-1-oxo-2-phenyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile

3-(2-aminoethylamino)-1-oxo-2-phenyl-1,2,4a,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile

(E/Z)-3-ethylimino-1-oxo-2-phenyl-1,2,3,5,6,7-hexahydropyrrolo[1,2-c]pyrimidine-4-carbonitrile