p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside

Base Information

• Chemical Name: p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside
• CAS No.: 950597-91-8
• Molecular Formula: C₆₁H₅₈O₁₂SSi
• Molecular Weight: 1043.28
• Mol file: 950597-91-8.mol

Synonyms:p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside

Chemical Property of p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside

There total 1 articles about p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H36Cl3NO7Si + p-toluyl 2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside (685111-68-6) → p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside (950597-91-8)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; In dichloromethane; at -30 - -5 ℃; for 0.416667h;

DOI:10.1021/ja072892+

Reference yield: 86.0%

p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside (950597-91-8) + 8-azidooctyl 2,3-di-O-benzoyl-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranoside → C119H115N3O31Si

Guidance literature:

With N-iodo-succinimide; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1021/ja072892+

Reference yield: 84.0%

p-tolyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside (950597-91-8) + 8-azidooctyl 2,3-di-O-benzoyl-5-α-D-arabinofuranoside → 8-azidooctyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranoside (950597-92-9)

Guidance literature:

With N-iodo-succinimide; 4 A molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at 0 ℃; for 0.333333h;

DOI:10.1021/ja072892+

upstream raw materials:

p-toluyl 2,3-di-O-benzoyl-1-thio-α-D-arabinofuranoside

Downstream raw materials:

8-azidooctyl 2,3-di-O-benzoyl-5-O-(tert-butyldiphenylsilyl)-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranosyl-(1->5)-2,3-di-O-benzoyl-α-D-arabinofuranoside