(S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol

Base Information

• Chemical Name: (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol
• CAS No.: 945215-23-6
• Molecular Formula: C₄₃H₅₆N₂O₄
• Molecular Weight: 664.929
• Mol file: 945215-23-6.mol

Synonyms:(S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol

Chemical Property of (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol

There total 4 articles about (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-O-(4-cyanophenyl)-2-O-tetradecyl-1-O-triphenylmethylglycerol (935852-03-2) → (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol (945215-23-6)

Guidance literature:

With hydroxylamine hydrochloride; potassium carbonate; In ethanol; for 18h; Heating;

DOI:10.1021/jm060082n

Reference yield:

(S)-3-O-(4-cyanophenyl)-1-O-triphenylmethylglycerol (935852-02-1) → (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol (945215-23-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 1 h / 20 °C

1.2: dimethylformamide / 12 h / 20 °C

2.1: hydroxylamine hydrochloride; K₂CO₃ / ethanol / 18 h / Heating

With hydroxylamine hydrochloride; sodium hydride; potassium carbonate; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm060082n

Reference yield:

4-cyanophenol (767-00-0) → (S)-3-O-[4-(N-hydroxylamidino)phenyl]-2-O-tetradecyl-1-O-triphenylmethylglycerol (945215-23-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: NaOEt / ethanol / 1 h / Heating

2.1: triethylamine; 4-(N,N-dimethylamino)pyridine / CH₂Cl₂ / 20 °C

3.1: NaH / dimethylformamide / 1 h / 20 °C

3.2: dimethylformamide / 12 h / 20 °C

4.1: hydroxylamine hydrochloride; K₂CO₃ / ethanol / 18 h / Heating

With dmap; hydroxylamine hydrochloride; sodium ethanolate; sodium hydride; potassium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm060082n

upstream raw materials:

(S)-3-O-(4-cyanophenyl)-2-O-tetradecyl-1-O-triphenylmethylglycerol

(S)-3-O-(4-cyanophenyl)-1-O-triphenylmethylglycerol

4-cyanophenol

(S)-3-(4-cyanophenoxy)-propane-1,2-diol