2-methyl-3-phenylsulphonylquinoxaline

Base Information

• Chemical Name: 2-methyl-3-phenylsulphonylquinoxaline
• CAS No.: 60638-86-0
• Molecular Formula: C₁₅H₁₂N₂O₂S
• Molecular Weight: 284.338
• Mol file: 60638-86-0.mol

Synonyms:2-methyl-3-phenylsulphonylquinoxaline

Chemical Property of 2-methyl-3-phenylsulphonylquinoxaline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-3-phenylsulphonylquinoxaline

There total 5 articles about 2-methyl-3-phenylsulphonylquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-chloro-3-methylquinoxaline (32601-86-8) + sodium benzenesulfonate (873-55-2) → 2-methyl-3-phenylsulphonylquinoxaline (60638-86-0)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; In acetonitrile; for 10h; Heating;

Reference yield: 70.4%

2-methyl-3-(phenylthio)quinoxaline (111339-51-6) → 2-methyl-3-phenylsulphonylquinoxaline (60638-86-0)

Guidance literature:

With dihydrogen peroxide; In acetic anhydride; at 20 ℃; for 10h;

Reference yield:

3-methyl-2-oxo-1,2-dihydroquinoxaline (14003-34-0) → 2-methyl-3-phenylsulphonylquinoxaline (60638-86-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / POCl₃; DMF / 0.75 h / Heating

2: 81 percent / triethylbenzylammonium chloride / acetonitrile / 10 h / Heating

With N-benzyl-N,N,N-triethylammonium chloride; N,N-dimethyl-formamide; trichlorophosphate; In acetonitrile;

upstream raw materials:

2-chloro-3-methylquinoxaline

sodium benzenesulfonate

2-methyl-3-(phenylthio)quinoxaline

3-methyl-2-oxo-1,2-dihydroquinoxaline

Downstream raw materials:

2-phenylsulphonyl-3-styrylquinoxaline

2-Benzenesulfonyl-3-[(E)-2-(2-chloro-phenyl)-vinyl]-quinoxaline

2-Benzenesulfonyl-3-[(E)-2-(4-fluoro-phenyl)-vinyl]-quinoxaline