C₃₇H₄₃Cl₃N₂O₁₅

Base Information

• Chemical Name: C₃₇H₄₃Cl₃N₂O₁₅
• CAS No.: 944060-21-3
• Molecular Formula: C₃₇H₄₃Cl₃N₂O₁₅
• Molecular Weight: 862.112
• Mol file: 944060-21-3.mol

Synonyms:C₃₇H₄₃Cl₃N₂O₁₅

Chemical Property of C₃₇H₄₃Cl₃N₂O₁₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₄₃Cl₃N₂O₁₅

There total 9 articles about C₃₇H₄₃Cl₃N₂O₁₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

C35H43NO15 + trichloroacetonitrile (545-06-2) → C37H43Cl3N2O15 (944060-21-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1055/s-2007-970766

Reference yield:

C36H46Cl3NO14Si → C37H43Cl3N2O15 (944060-21-3)

Guidance literature:

Multi-step reaction with 5 steps

1: Dess-Martin periodinane; NaHCO₃ / CH₂Cl₂ / 3 h / 20 °C

2: NaClO₂ / 2-methyl-propan-2-ol; aq. phosphate buffer; various solvent(s) / 12 h / 20 °C

3: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl; pyridine / CH₂Cl₂ / 4 h / 20 °C

4: trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

5: 79 percent / DBU / CH₂Cl₂ / 2 h / 0 °C

With pyridine; sodium chlorite; sodium hydrogencarbonate; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In phosphate buffer; dichloromethane; tert-butyl alcohol; 1: Dess-Martin oxidation;

DOI:10.1055/s-2007-970766

Reference yield:

C40H46Cl9NO17Si → C37H43Cl3N2O15 (944060-21-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 85 percent / Zn; Ac₂O; AcOH / tetrahydrofuran / 2.5 h / 20 °C

2: Dess-Martin periodinane; NaHCO₃ / CH₂Cl₂ / 3 h / 20 °C

3: NaClO₂ / 2-methyl-propan-2-ol; aq. phosphate buffer; various solvent(s) / 12 h / 20 °C

4: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl; pyridine / CH₂Cl₂ / 4 h / 20 °C

5: trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

6: 79 percent / DBU / CH₂Cl₂ / 2 h / 0 °C

With pyridine; sodium chlorite; acetic anhydride; sodium hydrogencarbonate; Dess-Martin periodane; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; zinc; In tetrahydrofuran; phosphate buffer; dichloromethane; tert-butyl alcohol; 2: Dess-Martin oxidation;

DOI:10.1055/s-2007-970766

upstream raw materials:

trichloroacetonitrile

C₂₈H₃₇Cl₃O₈Si

2-(Trimethylsilyl)ethyl 2,3-di-O-benzyl-β-D-glucopyranoside

(2R,3S,4R,5R,6S)-2-(acetoxymethyl)-6-(phenylthio)-5-(((2,2,2-trichloroethoxy)carbonyl)amino)tetrahydro-2H-pyran-3,4-diyl diacetate

Downstream raw materials:

C₄₉H₅₆NO₁₈P