(R)-4-(Fmoc-amino)-5-phenylpentanoic acid

Base Information

Chemical Name:(R)-4-(Fmoc-amino)-5-phenylpentanoic acid
CAS No.:269078-74-2
Molecular Formula:C26H25 N O4
Molecular Weight:415.489
Hs Code.:29242990
DSSTox Substance ID:DTXSID80373269
Wikidata:Q72477941
Mol file:269078-74-2.mol

Synonyms:269078-74-2;(R)-4-(Fmoc-amino)-5-phenylpentanoic acid;(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid;Fmoc-(R)-4-amino-5-phenylpentanoic acid;(4R)-4-({[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}AMINO)-5-PHENYLPENTANOIC ACID;SCHEMBL7198853;DTXSID80373269;MFCD01074522;AS-65279;(R)-4-(Fmoc-amino)-5-phenylpentanoic aci;CS-0179074;C15448;EN300-7379390;A877093;J-016604;(R)-4-(Fmoc-amino)-5-phenylpentanoic acid, >=97.0%;(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoicacid

Suppliers and Price of (R)-4-(Fmoc-amino)-5-phenylpentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Fmoc-(R)-4-amino-5-phenylpentanoicAcid
1g
$ 325.00

TRC
Fmoc-(R)-4-amino-5-phenylpentanoicAcid
250mg
$ 75.00

Medical Isotopes, Inc.
Fmoc-(R)-4-amino-5-phenylpentanoicacid
20 g
$ 1380.00

Crysdot
(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoicacid 95+%
5g
$ 798.00

American Custom Chemicals Corporation
(R)-4-(FMOC-AMINO)-5-PHENYLPENTANOIC ACID 95.00%
100MG
$ 179.55

American Custom Chemicals Corporation
(R)-4-(FMOC-AMINO)-5-PHENYLPENTANOIC ACID 95.00%
500MG
$ 870.75

Alichem
(R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoicacid
5g
$ 813.96

AK Scientific
Fmoc-(R)-4-amino-5-phenylpentanoicacid
5g
$ 2318.00

Total 8 raw suppliers

Chemical Property of (R)-4-(Fmoc-amino)-5-phenylpentanoic acid

Chemical Property:

Vapor Pressure:1.05E-18mmHg at 25°C
Melting Point:149-151℃
Refractive Index:1.616
Boiling Point:667.1°C at 760 mmHg
PKA:4.59±0.10(Predicted)
Flash Point:357.2°C
PSA：79.12000
Density:1.234
LogP:5.20560
Storage Temp.:2-8°C
XLogP3:4.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:415.17835828
Heavy Atom Count:31
Complexity:580

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-(R)-4-amino-5-phenylpentanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CCC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](CCC(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
Uses Fmoc-(R)-4-amino-5-phenylpentanoic Acid is a useful synthetic intermediate.

Technology Process of (R)-4-(Fmoc-amino)-5-phenylpentanoic acid

There total 3 articles about (R)-4-(Fmoc-amino)-5-phenylpentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 63328-06-3,916198-97-5
(4R)-4-amino-5-phenylpentanoic acid

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 269078-74-2
(R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid

Guidance literature:: With sodium carbonate; In tetrahydrofuran;
DOI:10.1039/c2ob26805a

Reference yield:

: 195867-20-0
(4S)-4-[(tert-butoxycarbonyl)amino]-5-phenylpentanoic acid

: 269078-74-2
(R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

2: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C / pH Ca_. 10

With sodium carbonate; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/cmdc.201700370

Reference yield:

: 139545-04-3
(E)-(S)-4-tert-Butoxycarbonylamino-5-phenyl-pent-2-enoic acid

: 269078-74-2
(R)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-phenylpentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: palladium on carbon; hydrogen / ethanol / 2 h / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 0.5 h / 0 °C

3: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C / pH Ca_. 10

With palladium on carbon; hydrogen; sodium carbonate; trifluoroacetic acid; In tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1002/cmdc.201700370