3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine

Base Information

Chemical Name:3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine
CAS No.:268547-53-1
Molecular Formula:C7H5 Br Cl N3
Molecular Weight:246.494
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30467521
Wikidata:Q82294494
Mol file:268547-53-1.mol

Synonyms:3-BROMO-7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE;268547-53-1;3-bromo-7-chloro-5-methyl-2H-pyrazolo[4,3-b]pyridine;SCHEMBL6851926;DTXSID30467521;AB43933;AT28826;3-bromo-7-chloro-5-methyl-2H-pyrazolo[4, 3-b]pyridine

Suppliers and Price of 3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95+%
1g
$ 510.00

Chemenu
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95%
1g
$ 482.00

American Custom Chemicals Corporation
3-BROMO-7-CHLORO-5-METHYL-1H-PYRAZOLO-[4,3-B]PYRIDINE 95.00%
5MG
$ 501.78

Alichem
3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine
1g
$ 411.84

AccelPharmtech
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 97.00%
5G
$ 4530.00

AccelPharmtech
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 97.00%
1G
$ 2640.00

Total 5 raw suppliers

Chemical Property of 3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine

Chemical Property:

Boiling Point:373.4±37.0 °C(Predicted)
PKA:6.91±0.40(Predicted)
PSA：41.57000
Density:1.857±0.06 g/cm3(Predicted)
LogP:2.68220
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:244.93554
Heavy Atom Count:12
Complexity:180

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(NN=C2C(=C1)Cl)Br

Technology Process of 3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine

There total 4 articles about 3-Bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-B]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 94220-38-9
7-chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine

: 268547-53-1
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: With bromine; In methanol; for 0.5h;
DOI:10.1021/jm049085v

Reference yield:

: 268547-52-0,94220-37-8
5-methyl-1H-pyrazolo[4,3-b]pyridine-7-ol

: 268547-53-1
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / phosphorus oxychloride / acetonitrile / 3 h / Heating

2: 98 percent / bromine / aq. methanol / 0.5 h

With bromine; trichlorophosphate; In methanol; acetonitrile;
DOI:10.1021/jm049085v

Reference yield:

: 3-(1H-pyrazol-4-ylamino)but-2-enoic acid ethyl ester

: 268547-53-1
3-bromo-7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / diphenyl ether / 220 °C

2: 95 percent / phosphorus oxychloride / acetonitrile / 3 h / Heating

3: 98 percent / bromine / aq. methanol / 0.5 h

With bromine; trichlorophosphate; In methanol; diphenylether; acetonitrile;
DOI:10.1021/jm049085v